In the fall of 2019, Schreiner MediPharm launched Cap-Lock, an innovative first-opening indication for prefilled syringes, followed by a product evolution less than a year later: The label now featured an RFID inlay integrated at the level of the cap enabling automated supply chain management plus digital first-opening indication. To optimize industrial manufacturing of the Cap-Lock cap adapter, Schreiner MediPharm was looking for a cooperation partner—and found it in Plas-Tech Engineering. As a result of this partnership, pharmaceutical manufacturers benefit from a full-service solution for equipping their luer-lock syringes with reliable tamper evidence.

Cap-Lock is a specialty security concept for prefilled syringes developed by Schreiner MediPharm that combines a cap adapter and label. A syringe sealed with Cap-Lock irreversibly indicates if the syringe has been opened before. This ensures the integrity of the primary container and prevents its undetected opening. Unlike shrink-wrap solutions, Cap-Lock is also suitable for heat-sensitive substances.

Specializing in customized prefillable polymer syringes and injection-molded parts, Plas- Tech Engineering develops and produces the cap adapters. The cap is precisely adapted to the syringe and ensures reliable interlinking with the primary closure to equalize the diameter differences between the syringe body and closure. The cap adapter can be realized in a variety of colors to emphasize desired branding. In addition, customization of the cap surface texture is available to support safety and ease of opening the syringe. Plas-Tech Engineering can deliver the syringe plus applied cap as a validated system.

Schreiner MediPharm designs the tamper-evident marking label to suit customer- and application-specific requirements. The label can be provided with additional functionalities such as counterfeit-protection features, detachable documentation labels, light protection and an integrated RFID chip. Thanks to Cap-Lock’s special construction, the label can be applied to the syringe in the normal labeling process.

Due to the collaboration and development partnership between Schreiner MediPharm and Plas-Tech Engineering, pharmaceutical manufacturers benefit from a full-service solution tailored to meet their specific needs.